[PDF] from u-psud.frJP Guilloux, DJ David, L Xia, HT Nguyen… - …, 2011 - Elsevier Selective serotonin (5-HT) re-uptake inhibitors (SSRIs) are commonly used in the treatment of generalized anxiety disorder in Humans. However, because only few animal models display overt anxious-like behavior, detailed preclinical studies of the anxiolytic properties of ... Cited by 2 - Related articles - Check for Full Text - All 4 versions
C Suzuki, C Miyamoto, T Furuyashiki, S Narumiya… - FEBS letters, 2011 - Elsevier We found that centrally administered prostaglandin (PG) E 2 exhibited anxiolytic-like activity in the elevated plus-maze and open field test in mice. Agonists selective for EP 1 and EP 4 receptors, among four receptor subtypes for PGE 2 , mimicked the anxiolytic-like activity of ... Check for Full Text - All 3 versions
[HTML] from nih.gov Check for Full TextM Cazorla, J Prémont, A Mann… - The Journal of clinical …, 2011 - ncbi.nlm.nih.gov The neurotrophin brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase B (TrkB) have emerged as key mediators in the pathophysiology of several mood disorders, including anxiety and depression. However, therapeutic compounds that ... Related articles - All 4 versions
Check for Full TextGV Carr, LE Schechter… - Psychopharmacology, 2011 - Springer Abstract Rationale Although selective serotonin reuptake inhibitors (SSRIs) produce clinical therapeutic effects on depression and anxiety through augmentation of serotonergic neuro- transmission, there is little known about the potential contributions of the 5-HT6 receptor ... Cited by 5 - Related articles - All 4 versions
Check for Full TextS Gaburro, O Stiedl, P Giusti… - … scientific journal of …, 2011 - Cambridge Univ Press Abstract Increasing evidence suggests that specific physiological measures may serve as biomarkers for successful treatment to alleviate symptoms of pathological anxiety. Studies of autonomic function investigating parameters such as heart rate (HR), HR variability and blood pressure (BP) ... Cited by 1 - Related articles - All 3 versions