[PDF] from epm.brK Conkrite, M Sundby, S Mukai… - Genes & …, 2011 - genesdev.cshlp.org The miR-17∼92 cluster is a potent microRNA-encoding oncogene. Here, we show that miR-17∼92 synergizes with loss of Rb family members to promote retinoblastoma. We observed miR-17∼92 genomic amplifications in murine retinoblastoma and high expression of miR- ... Cited by 1
Z Chen, JD Higgins, JTL Hui, J Li… - The EMBO …, 2011 - nature.com We have analysed the role of RBR (retinoblastoma related), the Arabidopsis homologue of the tumour suppressor Retinoblastoma protein (pRb), during meiosis. We characterise the rbr-2 mutation, which causes a loss of RBR in male meiocytes. The rbr-2 plants exhibit strongly ... Cited by 1 - Related articles - All 3 versions
[PDF] from yale.eduW Lin, J Cao, J Liu, ML Beshiri… - Proceedings of the …, 2011 - National Acad Sciences Aberrations in epigenetic processes, such as histone methylation, can cause cancer. Retinoblastoma binding protein 2 (RBP2; also called JARID1A or KDM5A) can demethylate tri- and dimethylated lysine 4 in histone H3, which are epigenetic marks for transcriptionally active chromatin, ...
H Sihto, H Kukko, V Koljonen, R Sankila… - Clinical Cancer …, 2011 - AACR Results: MCPyV LTA expression was strongly associated with presence of MCPyV DNA in tumor, and it was almost invariably associated with tumor RB expression (P < 0.0001 for both comparisons). Both MCC LTA and RB expression were strongly associated with favorable ... Related articles - All 2 versions
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