DA Nelson, SJ Singh, AB Young, MD Tolbert… - Drug and Alcohol …, 2011 - Elsevier ... While this common viralinfection is seldom life threatening, the immune status of the individual influences the severity and length of the acute illness. Furthermore, upon recovering from mononucleosis, EBV becomes latent and persists for the life of the individual. ... All 3 versions
J Loh, G Zhao, CA Nelson, P Coder, L Droit… - Journal of …, 2011 - Am Soc Microbiol ... To further investigate whether RHVP can establish latentinfection in splenocytes, we performed PCR using primers to RHVP ORF 50 to detect the presence of the viral genome in the same splenocyte and peritoneal cell samples analyzed in the ex vivo reactivation assays above ... Related articles - All 4 versions
M Carrington… - Annual Review of Immunology, 2011 - annualreviews.org ... and becomes detectable in plasma (Figure 3). Subsequent rapid viral replication in activated CD4 T cells and systemic spread lead to an exponential increase in plasma viral load, which reaches its peak 3–4 weeks after infection (15). By this time, latentviral reservoirs are ... Related articles
[HTML] from plos.orgJM Richner, K Clyde, AC Pezda, BYH Cheng… - PLoS pathogens, 2011 - dx.plos.org ... biphasic lifecycle comprised of a lytic replicative stage and a relatively dormant latent stage ... During a lytic gammaherpesvirus infection, cellular gene expression is severely compromised in a process ... In this study, we address the purpose of this activity in the viral lifecycle through ... Cached
V Vezys, P Penaloza-MacMaster… - The Journal of …, 2011 - Am Assoc Immnol ... Page 3. with transfer of transgenic virus-specific CD8 T cells, there is a 99% reduction of viral loads, as well as increased numbers of transferred T cells. ... 4-1BB 2/2 mice have reduced numbers of memory CD8 T cells during latent murine CMV infection, but paradoxically ... Related articles - All 2 versions
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