SS Devgan, O Sanal, C Doil, K Nakamura… - Cell Death & …, 2011 - nature.com Maintaining genomic integrity is critical to avoid life-threatening disorders, such as premature aging, neurodegeneration and cancer. A multiprotein cascade operates at sites of DNA double-strand breaks (DSBs) to recognize, signal and repair damage. RNF168 ... Cited by 5 - Related articles - All 3 versions
[PDF] from cnrs.frJ Bartek, S Devgan, C Doil, K Nakamura… - 2011 - peer.ccsd.cnrs.fr Page 1. 1 Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia ... consistent with the observed defective DNA damage checkpoints/repair and pronounced radiosensitivity. ...
YV Wang, M Leblanc, N Fox, JH Mao… - Genes & …, 2011 - genesdev.cshlp.org Cell cycle regulation in hematopoietic stem cells (HSCs) is tightly controlled during homeostasis and in response to extrinsic stress. p53, a well-known tumor suppressor and transducer of diverse stress signals, has been implicated in maintaining HSC quiescence and self-renewal. ... Related articles - All 2 versions
H Liu, X Sun, S Zhang, W Ge, Y Zhu… - … and oncology: journal …, 2011 - ncbi.nlm.nih.gov BACKGROUND: Tumor radioresistance often leads to treatment failure during radiotherapy. New strategies like developing radiosensitizer are clinically important. Intervention with DNA double-strand break repair is an effective way to modulate tumor cell radiosensitivity. This ... All 2 versions
沪公网安备号：31010402006960 （网站）31010405000484 （蝌蝌APP）
安全保密
