FR Schuster, B Hubner, M Führer… - Blood Cancer …, 2011 - nature.com One of the major obstacles of immunosuppressive therapy (IST) in children with severe aplastic anemia (SAA) comes from the often months-long unpredictability of bone-marrow (BM) recovery. In this prospective study in children with newly diagnosed very severe AA ... Related articles
JE Sanders, AE Woolfrey, PA Carpenter, BE Storer… - Blood, 2011 - ncbi.nlm.nih.gov Aplastic anemia (AA), a potentially fatal disease, may be cured with marrow transplantation. Survival in pediatric patients has been excellent early after transplant, but only limited data are available regarding late effects. This study evaluates late effects among 152 patients followed 1-38 ( ...
P Scheinberg, O Nunez, B Weinstein… - New England Journal …, 2011 - nejm.org A large, unexpected difference was observed in the rate of hematologic response at 6 months in favor of horse ATG (68%; 95% confidence interval [CI], 56 to 80) as compared with rabbit ATG (37%; 95% CI, 24 to 49; P<0.001). Overall survival at 3 years also differed, with a survival ...
JM Valdez, P Scheinberg, O Nunez… - Clinical Infectious …, 2011 - cid.oxfordjournals.org Results. During the past 2 decades, infection-related mortality decreased from 37% in group 1 to 11% in group 3 (P<.001), and the frequency of IFIs decreased from 49% in group 1 to 8% in group 3 (P<.001). Overall 5-year survival for all patients (n = 420) increased from 64% ... Cited by 3 - Related articles - All 4 versions
M Ahamed, MJ Akhtar, S Verma, A Kumar… - Bioscience …, 2011 - ncbi.nlm.nih.gov Concern about environmental lead exposure as a significant public health threat has increased as evidence has accumulated regarding adverse health effects at successively lower levels. Aplastic anemia is a hematological disorder of unknown etiology with a high lethality rate. ...
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