DS Hong, R Kurzrock, Y Oh, JJ Wheler… - Clinical Cancer …, 2011 - AACR ... Fifteen patients had progressive disease, and seven patients achieved stable disease (minimum of 6 weeks) as best ... and a lowest no observed-adverse-effectlevel (NOAEL) for LY2275796 was defined at 5 mg/kg in mice and 2 mg/kg in monkeys. ... Cited by 1
D Wexler… - The Journal of Clinical Pharmacology, 2011 - jcp.sagepub.com ... I). In designating the dose associated with the no observable adverseeffectlevel (NOAEL), investigators ...Observed mean (standard deviation) vs predicted values for human oral clearance (L/h ... are compared with both relative toxicity profiles and the minimum anticipated biologic ... Related articles - All 3 versions
[PDF] from icar.org.inP Das, SK Manna, SA Mastan… - Indian Journal of …, 2011 - epubs.icar.org.in ... Under adverse environmental conditions, synthesis of this protein (HSP-70) increases and they act to repair and ... In the present study, it has been observed that the concentration of HSP 70 in the ... the changed metabolism with the physical stress are minimum in these two organs. ... Related articles - All 2 versions
D Rathkopf, G Liu, MA Carducci… - Clinical Cancer …, 2011 - AACR ... The minimum efficacious exposure of the compound of 12.7 μmol/L h (AUC 0–24 ) was projected to occur in humans in the range of 60–80 mg/d ... Data points are observed data and the solid lines are the results of regression analysis. NOAEL, no observable adverseeffectlevel. ... Cited by 3 - Related articles - All 3 versions
P Dadhaniya, C Patel, J Muchhara… - Food and Chemical …, 2011 - Elsevier ... Analyses were conducted using two-tailed Student's “t” test for minimum significance levels of 5%, comparing Group I to Groups II, III and IV, and Group V to VI by sex. ... Similarly, in the recovery group also no adverse effects of the curcumin preparation were observed. ... All 2 versions
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