VA Narkar, W Fan, M Downes, RT Yu, JW Jonker… - Cell Metabolism, 2011 - Elsevier How type I skeletal muscle inherently maintains high oxidative and vascular capacity in the absence of exercise is unclear. We show that nuclear receptor ERRγ is highly expressed in type I muscle and, when transgenically expressed in anaerobic type II muscles (ERRGO mice), dually ... Cited by 2 - Related articles - All 2 versions
RA Cairns, IS Harris… - Nature Reviews Cancer, 2011 - nature.com Interest in the topic of tumour metabolism has waxed and waned over the past century of cancer research. The early observations of Warburg and his contemporaries established that there are fundamental differences in the central metabolic pathways operating in malignant tissue. ... Cited by 20 - Related articles - All 3 versions
L Guarente - Cell Metabolism, 2011 - Elsevier It is now apparent that a large number of cellular proteins are acetylated. For example, recent studies have uncovered acetylation of a high fraction of mitochondrial proteins (Kim et al., 2006), as well as most metabolic enzymes in the cytosolic/nuclear pool ([Wang et al., ...
H Liu, MM Fergusson, JJ Wu, II Rovira… - Science …, 2011 - ncbi.nlm.nih.gov The contribution of the Wnt pathway has been extensively characterized in embryogenesis, differentiation, and stem cell biology but not in mammalian metabolism. Here, using in vivo gain- and loss-of-function models, we demonstrate an important role for Wnt signaling in ... Cited by 1 - Related articles
MJ Potthoff, J Boney-Montoya, M Choi, T He… - Cell Metabolism, 2011 - Elsevier Regulation of hepatic carbohydrate homeostasis is crucial for maintaining energy balance in the face of fluctuating nutrient availability. Here, we show that the hormone fibroblast growth factor 15/19 (FGF15/19), which is released postprandially from the small intestine, inhibits ... Cited by 1 - All 2 versions
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