O Hardiman - Neurodegenerative Disorders, 2011 - Springer Abstract Amyotrophic lateral sclerosis or motor neuron disease is a progressive motor system degeneration. Extra motor involvement also occurs, primarily in the form of execu- tive dysfunction. Up to 15% of those with ALS also develop frontotemporal dementia. The ... Related articles - All 4 versions
WS Johnston, K Hoskins… - Neurology, 2011 - AAN Enterprises The patient's wife, Anne Smith, reports that her husband Glen has suffered weakness of the hands and then arms gradually over the last year. Three months ago, he consulted a neurologist, who performed numerous investigations, then told Glen he had ALS or Lou Gehrig's disease. ... Cited by 2 - Related articles
MC Kiernan, S Vucic, BC Cheah, MR Turner… - The Lancet, 2011 - Elsevier Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease of the human motor system. In this Seminar, we summarise current concepts about the origin of the disease, what predisposes patients to develop the disorder, and discuss why all cases of ... Cited by 8 - Related articles - All 7 versions
MR O'Brien, B Whitehead… - Amyotrophic Lateral …, 2011 - informahealthcare.com Our objectives were to explore the personal perspectives of the diagnostic experience for people with ALS/MND and their family carers identifying issues that could impact positively or negatively on these experiences. We conducted a qualitative study with face-to-face interviews to ... Cited by 1 - Related articles - All 3 versions
[PDF] from northwestern.eduR Benmohamed, AC Arvanites… - … Lateral Sclerosis, 2011 - informahealthcare.com The underlying cause of amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disorder, remains unknown. However, there is strong evidence that one pathophysiological mechanism, toxic protein misfolding and/or aggregation, may trigger motor neuron ... Cited by 2 - Related articles - All 4 versions
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