SC Boyle, M Kim, MT Valerius… - Development ( …, 2011 - ncbi.nlm.nih.gov The primary excretory organ in vertebrates is the kidney, which is responsible for blood filtration, solute homeostasis and pH balance. These functions are carried out by specialized epithelial cells organized into tubules called nephrons. Each of these cell types arise ...
T Samuel, MD Hughson, WE Hoy… - … Meeting of the …, 2011 - espace.library.uq.edu.au Background: Keller et al. described lower nephron numbers in 10 European adults with documented hypertension (NEJM, 2003) and Brenner et al. proposed earlier that nephron underendowment might be driving the hypertensive state (AJKD, 1995). We examined a larger series in the ... Cached
ME Wlodek, AL Mibus, A Tan… - … Origins of Health & …, 2011 - espace.library.uq.edu.au Wlodek, ME, Mibus, AL, Tan, A., Arena, D., Siebel, AL, Owens, JA and Moritz, KM (2007). Uteroplacental insufficiency causes growth restriction and a nephron deficit but no hypertension in female offspring with adequate postnatal nutrition preventing the nephron deficit. In: , Early Human ... Cached - All 4 versions
[PDF] from massgeneral.orgCQ Diep, D Ma, RC Deo, TM Holm, RW Naylor… - Nature, 2011 - nature.com Loss of kidney function underlies many renal diseases 1 . Mammals can partly repair their nephrons (the functional units of the kidney), but cannot form new ones 2, 3 . By contrast, fish add nephrons throughout their lifespan and regenerate nephrons de novo after injury 4, 5 , providing a ... Cited by 6 - Related articles - All 7 versions
RN Douglas-Denton, BJ McNamara… - Ethnicity and …, 2011 - espace.library.uq.edu.au The total number of nephrons in normal human kidneys varies over a 10-fold range. This variation in total nephron number leads us to question whether low nephron number increases the risk of renal disease in adulthood. This review considers the available evidence in humans ... Cited by 4 - Related articles - Cached - All 2 versions