DM Rosenbaum, C Zhang, JA Lyons, R Holl… - Nature, 2011 - nature.com G-protein-coupled receptors (GPCRs) are eukaryotic integral membrane proteins that modulate biological function by initiating cellular signalling in response to chemically diverse agonists. Despite recent progress in the structural biology of GPCRs 1 , the molecular basis for ... Cited by 26 - Related articles - All 6 versions
[PDF] from scienceinschool.orgT Warne, R Moukhametzianov, JG Baker, R Nehmé… - Nature, 2011 - nature.com The ligand-binding pockets are shown as viewed from the extracellular surface with EL2 removed for clarity (same colour scheme as in Fig. 1). a, β 2 AR with the antagonist carazolol bound (PDB code 2RH1); b, β 1 AR with the antagonist cyanopindolol bound (PDB code 2VT4); c, β 1 ... Cited by 23 - Related articles - All 7 versions
A Hiuge-Shimizu, N Maeda, A Hirata… - … , and vascular biology, 2011 - Am Heart Assoc Methods and Results— ob/ob mice, apolipoprotein E knockout (apoE KO) mice, and apoE and adiponectin double knockout mice were administered pioglitazone, Rivo, or no compound. Remarkable elevation of plasma adiponectin was observed, especially in Rivo-treated ob/ob mice. ... Cited by 1 - Related articles - All 4 versions
S Herberhold, C Coch, T Zillinger… - Antiviral …, 2011 - ncbi.nlm.nih.gov BACKGROUND: Upper respiratory tract infection is a frequent cause of morbidity worldwide. Although the course of infection is usually mild, it is responsible for enormous social and economic costs. Immunostimulation with bacterial extracts consisting of ribosomal RNA and ...
J Standfuss, PC Edwards, A D'Antona, M Fransen… - Nature, 2011 - nature.com G-protein-coupled receptors (GPCRs) comprise the largest family of membrane proteins in the human genome and mediate cellular responses to an extensive array of hormones, neurotransmitters and sensory stimuli. Although some crystal structures have been determined for GPCRs, ... Cited by 5 - Related articles - All 5 versions
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