WR Henderson, RC Oslund, JG Bollinger… - Journal of Biological …, 2011 - ASBMB Group X (GX) phospholipase A 2 , a member of a large group of secreted phospholipases A 2 (sPLA 2 s), has recently been demonstrated to play an important in vivo role in the release of arachidonic acid and subsequent formation of eicosanoids. In a Th2 cytokine-driven ...
TS Hallstrand, Y Lai, B Johnson… - American Journal of …, 2011 - Am Thoracic Soc University of Washington, Seattle, WA, University of Washington, Seattle, University of California, San Francisco, San Francisco, 1 2 3 ... University of California at Davis, Davis, CA ... Patients with exercise-induced bronchoconstriction (EIB) have increased levels of ... All 3 versions
X Huang, M Kudo, A Melton, X Ren… - American Journal of …, 2011 - Am Thoracic Soc UCSF, Mission Bay, San Francisco, CA, University of California San Francisco, San Francisco, CA, UCSF, San Francisco, UCSF Mission Bay, 1 2 ... Asthma is a complex chronic inflammatory disease affecting millions of people worldwide. It is well accepted that Th2 ... All 3 versions
SNP Kelada, D Aylor, U Tavarez… - Proceedings of the …, 2011 - Am Thoracic Soc We aim to identify interactions between genes and allergen ex- posure that are relevant to the development of asthma in humans using a mouse model. To accomplish this, we first developed a new mouse using house dust mite (HDM) allergen that recapitulates key features of ... All 2 versions
C Perkins, N Yanase, G Smulian… - The Journal of …, 2011 - jem.rupress.org Production of the cytokines IL-4 and IL-13 is increased in both human asthma and mouse asthma models, and Stat6 activation by the common IL-4/IL-13R drives most mouse model pathophysiology, including airway hyperresponsiveness (AHR). However, the precise ... Cited by 2 - Related articles - All 3 versions