M Sudol - Oncogene, 2011 - nature.com Plasminogen activator (PLAU) is a serine protease that converts plasminogen to plasmin, a general protease, which promotes fibrinolysis and degradation of extracellular matrix. PLAU was reported in 1970s as one of the robustly induced enzymatic activities in Rous sarcoma virus (RSV)- ... Related articles - All 3 versions
B Testoni, V Schinzari, F Guerrieri… - Oncogene, 2011 - nature.com The DNp73 proteins act as trans-repressors of p53 and p73-dependent transcription and exert both anti-apoptotic activity and pro-proliferative activity. DNp73s are frequently up-regulated in a variety of human cancers, including human hepatocellular carcinomas (HCCs). ... Related articles - All 3 versions
H Jäkel, C Weinl… - Oncogene, 2011 - nature.com Janus kinase 2 (JAK2) couples ligand activation of cell surface cytokine receptors to the regulation of cellular functions including cell cycle progression, differentiation and apoptosis. It thereby coordinates biological programs such as development and hematopoiesis. Unscheduled ... All 3 versions
LMP Vinnedge, R McClaine, PK Wagh… - Oncogene, 2011 - nature.com Breast cancer is a major cause of cancer-related deaths in American women; therefore, the identification of novel breast cancer-related molecules for the discovery of new markers and drug targets remains essential. The human DEK gene, which encodes a chromatin-binding protein and DNA ... All 3 versions
M Thomas, K Lange-Grünweller, U Weirauch… - Oncogene, 2011 - nature.com The constitutively active serine/threonine kinase Pim-1 is upregulated in different cancer types, mainly based on the action of several interleukines and growth factors at the transcriptional level. So far, a regulation of oncogenic Pim-1 by microRNAs (miRNAs) has not been ... Cited by 1 - Related articles - All 3 versions
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