M Alvarez-Fernandez, VA Halim, M Aprelia… - Journal of Biological …, 2011 - ASBMB The forkhead transcription factor FoxM1 controls expression of a large number of genes that are specifically expressed during the G2 phase of the cell cycle. Throughout most of the cell cycle, FoxM1 activity is restrained by an auto-inhibitory mechanism, involving a repressor ...
NM Niemi, NJ Lanning, JA Klomp… - … and Cellular Biology, 2011 - Am Soc Microbiol Evasion of apoptosis is a significant problem affecting an array of cancers. In order to identify novel regulators of apoptosis, we performed an RNA interference (RNAi) screen against all kinases and phosphatases in the human genome. We identified MK-STYX (STYXL1), a ... Related articles - All 2 versions
A Singh, JM Redden, MS Kapiloff… - Molecular …, 2011 - ASPET Inhibitor-1 (I-1) is phosphorylated on threonine residue 35 (Thr35) by the cAMP-dependent protein kinase (PKA), inducing the potent inhibition of the serine-threonine-specific protein phosphatase 1 (PP1). We now report that the formation of a signaling complex containing PKA and I-1 ... Related articles
M Maheswaranathan, H Gole, I Fernandez… - Journal of Biological …, 2011 - ASBMB Alejandra San Martín Emory University Division of Cardiology 319 WMB 1639 Pierce Dr. Atlanta, GA 30322 Telephone: 404-727-3415 Fax: 404-727-3585 e-mail: asanmartin@emory.edu ... Keywords: Cytoskeleton, NADPH oxidase, protein ...
RJ Dickinson, L Delavaine, R Cejudo-Marin… - Journal of Biological …, 2011 - ASBMB Phosphorylation of the kinase interaction motif in MAP kinase phosphatase-4 mediates crosstalk between the protein kinase-A and MAP kinase signalling pathways. ...