J Sun, GK Sukhova, J Zhang, H Chen… - … and Vascular Biology, 2011 - Am Heart Assoc Objective—The development of abdominal aortic aneurysms (AAA) requires extensive aortic wall matrix degradation. Human AAA lesions express high levels of cathepsin L (CatL), one of the most potent mammalian elastases. Whether this protease participates directly in AAA ...
U Lim, T Ernst, SD Buchthal, M Latch… - Nutrition & …, 2011 - nature.com In the Multiethnic Cohort Study, Japanese Americans (JA) have lower mean body mass index (BMI) compared with Caucasians, but show a higher waist-to-hip ratio at similar BMI values and a greater risk of diabetes and obesity-associated cancers. ... We investigated the ... Related articles
J Sun, GK Sukhova, J Zhang, H Chen… - … and Vascular Biology, 2011 - Am Heart Assoc Objective—Cathepsin K (CatK) is one of the most potent mammalian elastases. We have previously shown increased expression of CatK in human abdominal aortic aneurysm (AAA) lesions. Whether this protease participates directly in AAA formation, however, remains unknown. Methods ...
[PDF] from uky.eduEHC Tang, E Shvartz, K Shimizu… - … , and vascular biology, 2011 - Am Heart Assoc Methods and Results— Prostaglandin E 2 (PGE 2 ) through activation of EP4, can mute inflammation. Hypercholesterolemic low-density lipoprotein receptor knockout (LDLR –/– ) mice transplanted with either EP4 +/+ (EP4 +/+ /LDLR –/– ) or EP4 –/– (EP4 –/– /LDLR –/– ) ... Cited by 3 - Related articles - All 5 versions
S Yusuf… - The Lancet, 2011 - thelancet.com Second, regression dilution bias will affect the hazard ratio of waist-to-hip ratio to a greater degree than for BMI. The regression dilution ratio is 0·95 for BMI, indicating that the adjusted hazard ratio will be very close to the unadjusted value of 1·07, whereas with a regression dilution ... Cached