C Li, N Narkbunnam, RJ Samulski, A Asokan… - Gene Therapy, 2011 - nature.com Recombinant adeno-associated virus (rAAV) is a promising gene delivery vector and has recently been used in patients with hemophilia. One limitation of AAV application is that most humans have experienced wild-type AAV serotype 2 exposure, which frequently generates ... All 3 versions
O Alpan, T Kamala, P Matzinger… - US Patent 7,867,974, 2011 - Google Patents Illllllllllllllllllllllllllllllllllllllllllllllllll US007867974B2 (12) United States Patent Alpan et al. (io) Patent No.: (45) Date of Patent: US 7,867,974 B2 Jan. 11,2011 (54) INDUCTION OF TOLERANCE BY ORAL ADMINISTRATION OF FACTOR VIII AND TREATMENT OF HEMOPHILIA (75) ... Related articles - All 4 versions
[HTML] from hematologylibrary.orgCRM Hay, B Palmer, E Chalmers… - …, 2011 - bloodjournal.hematologylibrary.org The age-adjusted incidence of new factor VIII inhibitors was analyzed in all United Kingdom patients with severe hemophilia A between 1990 and 2009. Three hundred fifteen new inhibitors were reported to the National Hemophilia Database in 2528 patients with severe ... Cited by 2 - Related articles - All 3 versions
S Lison, M Spannagl… - The Annals of thoracic …, 2011 - Soc Thorac Surgeons Patients with hemophilia A have a congenital defect in thrombin generation. Only limited data are available on the substitution regimens in hemophilia A patients during and after cardiac operations. There are no data on heparinization of these patients during cardiopulmonary ... Related articles - All 4 versions
[HTML] from hematologylibrary.orgNBY Tsui, RA Kadir, KC Chan, C Chi… - …, 2011 - bloodjournal.hematologylibrary.org Hemophilia is a bleeding disorder with X-linked inheritance. Current prenatal diagnostic methods for hemophilia are invasive and pose a risk to the fetus. Cell-free fetal DNA analysis in maternal plasma provides a noninvasive mean of assessing fetal sex in such pregnancies. ... Cited by 2 - Related articles - All 3 versions