RK Sachs, K Johnsson, P Hahnfeldt, J Luo, A Chen… - Cancer research, 2011 - AACR Chronic myeloid leukemia (CML) is characterized by a specific chromosome translocation, and its pathobiology is considered comparatively well understood. Thus, quantitative analysis of CML and its progression to blast crisis may help elucidate general mechanisms of ... Cited by 1 - Related articles - All 4 versions
V Najfeld, N Wisch, J Mascarenhas, L Issa… - Cancer Genetics, 2011 - Elsevier ... Abbreviations: AML, acute myeloid leukemia; BC, blastcrisis; CP, chronic phase; F, female; HU, hydroxyurea; INFα, interferon α; M, male; NA, not available; Ph, Philadelphia chromosome; Tx, treatment. a Interphase FISH showed >90% cells with BCR–ABL1 fusion. ... Related articles - All 3 versions
K Sakai, Y Ishikawa, Y Mori, M Kobayashi… - International journal of …, 2011 - Springer Abstract BCR-ABL kinase domain mutations were sequentially analyzed in a patient with chronic myeloid leukemia (CML) who exhibited repeated B-lymphoid blast crisis (CML-BC) during treatment with imatinib and dasatinib. We first identified five mutant BCR-ABL clones: Y253H, ... Cited by 1 - Related articles - All 3 versions
V Grossmann, A Kohlmann, M Zenger, S Schindela… - Leukemia, 2011 - nature.com Blast crisis (BC) is the terminal phase of chronic myeloid leukemia (CML) and is characterized by a rapid expansion of myeloid or lymphoid differentiation-arrested blast cells leading to short median survival. 1, 2 In approximately 70% of cases the blast lineage is myeloid, whereas ... Cited by 1 - Related articles - All 4 versions
C Matte-Martone, S Venkatesan… - The Journal of …, 2011 - Am Assoc Immnol Graft-versus-leukemia (GVL) against chronic-phase chronic myelogenous leukemia (CP-CML) is potent, but it is less efficacious against acute leukemias and blast-crisis chronic myelogenous leukemia (BC-CML). The mechanisms underlying GVL resistance are ...
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