AR Fathi, RM Pluta, KD Bakhtian, M Qi… - Journal of …, 2011 - thejns.org Subarachnoid hemorrhage (SAH)-induced vasospasm is a significant underlying cause of aneurysm rupture-related morbidity and death. While long-term intravenous infusion of sodium nitrite (NaNO 2 ) can prevent cerebral vasospasm after SAH, it is not known if the intravenous ...
DB Casey - 2012 - gradworks.umi.com The purpose of the research presented is to develop a better understanding of the mechanism by which nitrite is converted to nitric oxide. In the present study, the role xanthine oxidoreductase (XOR) and mitochondrial aldehyde dehydrogenase (mALDH2) plays in the mediation of ... Cached
[HTML] from plos.orgRM Pluta, EH Oldfield, KD Bakhtian, AR Fathi… - PloS one, 2011 - dx.plos.org The maximal tolerated dose for intravenous infusion of sodium nitrite was 267 µg/kg/hr. Dose limiting toxicity occurred at 446 µg/kg/hr. Toxicity included a transient asymptomatic decrease of mean arterial blood pressure (more than 15 mmHg) and/or an asymptomatic increase ... Cited by 1 - Related articles - Cached - All 6 versions
TE Ingram, RA Bleasdale, C Templeton, C Williams… - Heart, 2011 - heart.bmj.com Introduction Sodium nitrite (NaNO 2 ) became a popular means of treating angina in the 19th century, as its stable chemical structure allowed for cheap preparation and easy storage. However, the effects were slow and unpredictable and so it fell out of favour as more ...
AK Yadav, SF Doran, AA Samal… - American Journal of …, 2011 - Am Physiological Soc Nitrite (NO 2 − ) has been shown to limit injury to the heart, liver, and kidneys in various models of ischemia-reperfusion injury. Potential protective effects of systemic NO 2 − in limiting lung injury or enhancing repair have not been documented. We assessed the efficacy and ... Related articles - All 4 versions
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