R Krencik, JP Weick, Y Liu, ZJ Zhang… - Nature Biotechnology, 2011 - nature.com ... RA, retinoicacid. ... (c) Temporal course comparison of S100β (120 d, P = 0.0055) and GFAP (120 d, P = 0.001; 180 d, P = 0.0066) expression of retinoicacid– and FGF8-specified astroglia (from three separate passages of the H9 hESC line) among total cells. ... Cited by 2 - Related articles - All 3 versions
JA Hall, JL Cannons, JR Grainger, LM DosáSantos… - Immunity, 2011 - Elsevier Vitamin A and its metabolite, retinoic acid (RA) are implicated in the regulation of immune homeostasis via the peripheral induction of regulatory T cells. Here we showed RA was also required to elicit proinflammatory CD4 + helper T cell responses to infection and mucosal vaccination. ... Cited by 8 - All 2 versions
JA Hall, JR Grainger, SP Spencer… - Immunity, 2011 - Elsevier Vitamin A elicits a broad array of immune responses through its metabolite, retinoic acid (RA). Recent evidence indicates that loss of RA leads to impaired immunity, whereas excess RA can potentially promote inflammatory disorders. In this review, we discuss recent ...
K Pino-Lagos, Y Guo, C Brown… - The Journal of …, 2011 - jem.rupress.org It is known that vitamin A and its metabolite, retinoic acid (RA), are essential for host defense. However, the mechanisms for how RA controls inflammation are incompletely understood. The findings presented in this study show that RA signaling occurs ...
SSW Chung, X Wang… - Endocrine Reviews, 2011 - Endocrine Soc It has been recognized for decades that dietary retinol (vitamin A) and its physiologically active metabolite all-trans-retinoic acid are essential for normal spermatogenesis 1-4 . Given the importance of retinoic acid receptor alpha (RARα) in particular in regulating spermatogenesis 5-8 , ...