C Latchoumycandane, V Anantharam, H Jin… - Toxicology and Applied …, 2011 - Elsevier The neurotoxicant 6-hydroxydopamine (6-OHDA) is used to investigate the cellular and molecular mechanisms underlying selective degeneration of dopaminergic neurons in Parkinson's disease (PD). Oxidative stress and caspase activation contribute to the 6-OHDA-induced apoptotic ...
LV Dishaw, CM Powers, IT Ryde… - Toxicology and Applied …, 2011 - Elsevier Organophosphate flame retardants (OPFRs) are used as replacements for the commercial PentaBDE mixture that was phased out in 2004. OPFRs are ubiquitous in the environment and detected at high concentrations in residential dust, suggesting widespread human exposure. ... Cited by 1 - Related articles - All 2 versions
PRS Kodavanti, C Osorio, JE Royland… - Toxicology and Applied …, 2011 - Elsevier The vast literature on the mode of action of polychlorinated biphenyls (PCBs) indicates that PCBs are a unique model for understanding the mechanisms of toxicity of environmental mixtures of persistent chemicals. PCBs have been shown to adversely affect psychomotor function ...
FO Johnson, Y Yuan, RK Hajela, A Chitrakar… - … of Pharmacology and …, 2011 - ASPET Preliminary reports of portions of this project were presented previously: Johnson FO, Atchison WD, and Chitrakar A. (2010) Chronic methylmercury exposure potentiates [Zn 2+ ] 1 in motor neurons of hSOD1 mice, at the Annual Meeting of the Society of Toxicology; 2010 March ...
FO Johnson, Y Yuan, RK Hajela, DM Parsell… - … of Pharmacology and …, 2011 - ASPET Page 1. JPET 174466 1 Exposure to an Environmental Neurotoxicant Hastens the Onset of ALS-Like Phenotype in hSOD1G93A Mice: Glutamate-Mediated Excitotoxicity ... genetically- susceptible organism by exposure to low concentrations of an environmental neurotoxicant. ... Related articles - All 2 versions
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