[PDF] from molecular-cancer.comJD Prescott, JM Poczobutt, JJ Tentler… - Molecular …, 2011 - molecular-cancer.com ... directly test whether cytoplasmically restricted SAR protein is sufficient to initiate transformation. To this end, we generated two independent stable MCF-12A transfectant cell populations for GFP-NES1-SAR. As negative controls ... View as HTML
Z Zhang, X Wang, S Cheng, L Sun, Y Son… - Toxicology and Applied …, 2011 - Elsevier ... DLD1 cells were treated with arsenic, SOD and catalase for up to 2 weeks as described in the “Celltransformation assay” section. The cells were used to test their tumorigenicity in nude mice. ... To test if ROS are involved in the arsenic-induced celltransformation (Fig. ...
A Sakai, K Sasaki, K Hayashi, D Muramatsu… - … /Genetic Toxicology and …, 2011 - Elsevier ... In vitro celltransformation assays can supplement commonly used short-term test batteries and provide for the ability to identify chemical carcinogens that fail to induce genotoxic responses and would otherwise yield false negative results in genotoxicity tests [2], [3], [4] and [5]. A ... Cited by 1
S Lecosnier, C Cordier, P Simon, JC François… - The FASEB Journal, 2011 - FASEB ... IGF-1R is crucial for malignant transformation (42); therefore, we assessed the effects of PNA 959 on celltransformation. Anchorage-independent growth in the semisolid medium of soft agar is a strong indicator of the transformed phenotype and a stringent test of mitogenic ... Related articles - All 3 versions
F Chik… - Carcinogenesis, 2011 - Oxford Univ Press ... To test this hypothesis, we determined whether DNA demethylation in the presence of 5-azaCdR continued after 48 h, a time ... When celltransformation was measured, DNMT1 depletion had the strongest inhibitory effect and that was not enhanced by a triple depletion (Figure 5C ... Cited by 2 - Related articles - All 5 versions
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