S Kümper… - Cancer Cell, 2011 - Elsevier Tissues consist of cells and extracellular matrix (ECM), and cells are tightly linked to their extracellular environment through adhesion receptors such as integrins. Within a tissue, remodeling of the ECM can occur as part of normal physiological processes or in disease. ECM remodeling ... All 2 versions
MS Samuel, JI Lopez, EJ McGhee, DR Croft… - Cancer cell, 2011 - Elsevier Tumors and associated stroma manifest mechanical properties that promote cancer. Mechanosensation of tissue stiffness activates the Rho/ROCK pathway to increase actomyosin-mediated cellular tension to re-establish force equilibrium. To determine how actomyosin tension affects ... Cited by 1 - Related articles - All 3 versions
H Wolfenson, A Bershadsky, YI Henis… - Journal of Cell …, 2011 - jcs.biologists.org Focal adhesions (FAs) have key roles in the interaction of cells with the extracellular matrix (ECM) and in adhesion-mediated signaling. These dynamic, multi-protein structures sense the ECM both chemically and physically, and respond to external and internal forces by ... Cited by 2 - Related articles - All 3 versions
[PDF] from stowers-institute.orgMP Stewart, J Helenius, Y Toyoda, SP Ramanathan… - Nature, 2011 - nature.com During mitosis, adherent animal cells undergo a drastic shape change, from essentially flat to round 1, 2, 3 . Mitotic cell rounding is thought to facilitate organization within the mitotic cell and be necessary for the geometric requirements of division 4, 5, 6, 7 . However, the forces ... Cited by 12 - Related articles - All 9 versions
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