W Tan, W Zhang, A Strasner, S Grivennikov… - Nature, 2011 - nature.com Inflammatory mechanisms influence tumorigenesis and metastatic progression even in cancers whose aetiology does not involve pre-existing inflammation or infection, such as breast and prostate cancers 1 . For instance, prostate cancer metastasis is associated with the infiltration of ... Cited by 12 - Related articles - All 4 versions
G Francia, W Cruz-Munoz, S Man, P Xu… - Nature Reviews …, 2011 - nature.com An enduring problem in cancer research is the failure to reproduce highly encouraging preclinical therapeutic findings using transplanted or spontaneous primary tumours in mice in clinical trials of patients with advanced metastatic disease. There are several reasons for this, ... Cited by 10 - Related articles - All 4 versions
EM Slorach, J Chou… - Genes & Development, 2011 - genesdev.cshlp.org Amplification of 8p11-12 in human breast cancers is associated with increased proliferation and tumor grade and reduced metastasis-free patient survival. We identified Zeppo1 (zinc finger elbow-related proline domain protein 1) (FLJ14299/ZNF703) within this amplicon as a ... Cited by 2 - Related articles - All 3 versions
[HTML] from pnas.orgS Hiratsuka, DG Duda, Y Huang… - Proceedings of the …, 2011 - National Acad Sciences Increasing evidence suggests that myeloid bone marrow-derived cells (BMDCs) play a critical role in lung metastasis. Blockade of VEGF receptor 1 (VEGFR1) has been proposed as a potential strategy to limit myeloid BMDC recruitment to tumors. However, preclinical evidence ... Cited by 4 - Related articles - All 5 versions
BZ Qian, J Li, H Zhang, T Kitamura, J Zhang… - Nature, 2011 - nature.com Macrophages, which are abundant in the tumour microenvironment, enhance malignancy 1 . At metastatic sites, a distinct population of metastasis-associated macrophages promotes the extravasation, seeding and persistent growth of tumour cells 2 . Here we define the origin ... Cited by 6 - Related articles - All 3 versions
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