E Mignot - Narcolepsy, 2011 - Springer Low levels of the neuropeptide hypocretin-1 (hcrt-1, also called orexin-A) are found in the cerebrospinal fluid (CSF) of most people with narcolepsy with cataplexy and in some without cataplexy [1–6]. As a result, in the most recent revision of the International Classification of Sleep ...
HP Landolt - Narcolepsy, 2011 - Springer Many functional aspects of wakefulness and sleep, including excessive daytime sleepiness, vigilance, attention, sleep structure, and quantita- tive measures derived from the electroencephalo- gram (EEG) are tightly controlled by two interacting processes: (1) a ...
Y Dauvilliers… - Narcolepsy, 2011 - Springer Narcolepsy with cataplexy is a disabling disorder characterized by excessive daytime sleepiness (EDS) and abnormal rapid eye movement (REM) sleep manifestations including cataplexy (sudden loss of muscle tone triggered by strong emotions), sleep paralysis, hypnagogic ...
C Alexandre… - Narcolepsy, 2011 - Springer Over 60 years ago, researchers discovered that a blood-borne substance increased vascular tone and intestinal motility by constricting smooth muscle. They named this substance serotonin based on the Latin word serum and the Greek word tonic, and soon after, this factor was ...
M Lecendreux - Narcolepsy, 2011 - Springer Narcolepsy is a chronic primary sleep-wake disor- der, characterized by excessive daytime sleepiness (EDS), sudden sleep episodes, and attacks of mus- cle atonia mostly triggered by emotions (cata- plexy). Narcolepsy is a lifelong disorder, however, not progressive, and occurrence ...
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