E Aragón, N Goerner, AI Zaromytidou… - Genes & …, 2011 - genesdev.cshlp.org When directed to the nucleus by TGF-β or BMP signals, Smad proteins undergo cyclin-dependent kinase 8/9 (CDK8/9) and glycogen synthase kinase-3 (GSK3) phosphorylations that mediate the binding of YAP and Pin1 for transcriptional action, and of ubiquitin ligases Smurf1 and ... Cited by 1 - Related articles - All 2 versions
AM Kelley, PA Fay, HW Polley, RA Gill… - Ecosphere, 2011 - Eco Soc America Rising atmospheric CO 2 concentrations can alter carbon and nutrient cycling and microbial processes in terrestrial ecosystems. One of the primary ways microbes interact with soil organic matter is through the production of extracellular enzymes, which break down complex ...
AM Thomas, N Bui, JR Perkins, LA Yuva-Paylor… - …, 2011 - Springer Abstract Rationale Studies in the Fmr1 knockout (KO) mouse, a model of fragile X syndrome (FXS), suggest that excessive signaling through group I metabotropic glutamate receptors (mGluRs), comprised of subtypes mGluR1 and mGluR5, may play a role in the ... Related articles - All 2 versions
M Vicente-Manzanares, K Newell-Litwa… - The Journal of Cell …, 2011 - jcb.rupress.org Migratory front–back polarity emerges from the cooperative effect of myosin IIA (MIIA) and IIB (MIIB) on adhesive signaling. We demonstrate here that, during polarization, MIIA and MIIB coordinately promote localized actomyosin bundling, which generates large, stable adhesions that do ... Cited by 1 - Related articles - All 3 versions
AII Zaromytidou - Nature Cell Biology, 2011 - nature.com The liver responds to insulin by blocking gluconeogenesis and stimulating lipogenesis. Insulin-induced lipid synthesis requires induction of the transcription factor SREBP1c, which is mediated by the activation of mTORC1 (mammalian target of rapamycin complex 1), ...