KG Wolter - 2012 - gradworks.umi.com Metastatic melanoma has proven exceptionally difficult to treat, in part due to consistent defects in cell death pathways. The overexpression of antiapoptosis proteins from the Bcl-2 family is a hallmark of melanoma progression. Past strategies targeting these proteins have ... Cached
JA Freedman, DS Tyler, JR Nevins… - The American Journal of …, 2011 - Elsevier A defining characteristic of most human cancers is heterogeneity, resulting from the somatic acquisition of a complex array of genetic and genomic alterations. Dissecting this heterogeneity is critical to developing an understanding of the underlying mechanisms of disease and to paving ... Related articles - All 4 versions
RN Shore, P Shore, NM Monahan… - Journal of drugs in …, 2011 - ncbi.nlm.nih.gov Objective: To determine the effectiveness of a serial screening program in achieving early detection and preventing death in patients at increased risk for melanoma. Design: Retrospective study. Setting: Private dermatology practice. Patients: The study included all patients at ...
N McCarthy - Nature Reviews Cancer, 2011 - nature.com Malignant melanoma remains a difficult cancer to treat owing to its aggressive nature and frequent resistance to chemotherapeutic drugs. Sunburn during childhood has been associated with increased risk of melanoma development, and in a recent Nature paper, M. ... To read this article in ... All 3 versions
M Berwick - Melanoma Development, 2011 - Springer Abstract Melanoma is steadily increasing in incidence while mortality is steady or only increasing slightly. Patterns of incidence, including anatomic site, differ by age and sex as well as geographic location. Light pigmentation and multiple nevi are critical risk factors for the development ... Cited by 72 - Related articles - BL Direct - All 6 versions
沪公网安备号：31010402006960 （网站）31010405000484 （蝌蝌APP）
安全保密
