L Bédouet, F Pascale, M Bonneau, M Wassef… - Toxicology in Vitro, 2011 - Elsevier Intra-articular drug delivery systems (DDS) are envisaged as interesting alternative to locally release nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen to reduce pain in patients with osteoarthritis. The present study examines the toxicity of (S)-ibuprofen on ...
S Serratì, F Margheri, A Chillà… - Arthritis & …, 2011 - Wiley Online Library ... Interstitial collagenase (matrix metallo- proteinase 1) associated with the plasma membrane of both neoplastic and nonneoplastic cells. ... Synovial fibroblasts ... 2009;15:1414-20 29. Hamilton JA and Slyvka J. Stimulation of human synovial fibroblast plasminogen activator ... Related articles - All 2 versions
A Crilly, SE Robertson, JH Reilly… - Annals of the …, 2011 - ard.bmj.com Results All PDE4 inhibitors dose-dependently reduced the release of TNFα from primary synovial membrane cultures (n=5), half maximal inhibitory concentration (IC 50 ) 300–30 nM, p<0.05. Similarly, a significant suppression in the release the proinflammatory chemokines, ... Related articles - All 5 versions
S Finnegan, S Clarke, D Gibson… - Annals of the …, 2011 - ard.bmj.com Results Synovial hyperplasia varied significantly between the three groups (p<0.0001). There was a significant difference in the CD3 T-cell population between the three groups (p=0.004) and between the extended-to-be and persistent group (p=0.032). CD4 expression was ... Related articles - All 2 versions
E Domenech… - … of Ultrasound in …, 2011 - Am inst Ulrrasound Med Methods—Twenty-one New Zealand White rabbits (42 knees) were used in this study. We injected the knees with normal saline (saline group; n = 21) and SonoVue (SonoVue group; n = 21). A histologic examination of the knees was performed out at 3 and 12 hours and 3, 7, 15, 30, ...