G Kozlov, AY Denisov, M Girard, MJ Dicaire… - Journal of Biological …, 2011 - ASBMB ... The C terminus of the protein contains an HEPN (higher eukaryotes and prokaryotes nucleotide-binding) domain of unknown function. Here, we determined the high-resolution 1.9-Å crystal structure of the HEPN domain from human sacsin. ... Related articles
[PDF] from biomedcentral.comS Maruyama, T Suzaki, A Weber… - BMC Evolutionary …, 2011 - biomedcentral.com ... symbiogenesis: ymbiogenesis: ymbiogenesis: euglenoid, uglenoid, uglenoid, dinoflagellate, and inoflagellate, and inoflagellate, and sporozoan porozoan porozoan plastid origins and the eukaryote ukaryoteukaryote family tree. J Eukaryot Microbiol 1999, 46(4):347-366. ... Related articles - All 4 versions
AM Martelli, C Evangelisti, W Chappell, SL Abrams… - Leukemia, 2011 - nature.com ... The mTOR complex1 (mTORC1) regulates the assembly of the eukaryotic initiation factor4F complex, which is critical for the translation of mRNAs that are important for cell growth, prevention of apoptosis and transformation. ... Cited by 1 - Related articles - All 3 versions
M Mollapour… - Biochimica et Biophysica Acta (BBA)-Molecular …, 2011 - Elsevier ... Heat shock protein 90 (H sp90) is an essential e ukaryotic mol ecular c haperone that c arries out these p rocesses in normal and cancer c ells. ... (1) The e xtent of Hsp90 p ost-translational modi fications is greater in metazoans compared to single cell e ukaryotes, suggesting that ...
[HTML] from nih.govLS Steelman, WH Chappell, SL Abrams… - Aging (Albany …, 2011 - ncbi.nlm.nih.gov ... It regulates translation in response to nutrients and growth factors by phosphorylating components of the protein synthesis machinery, including p70 S6K and eukaryoticinitiation factor (eIF)-4Ebinding protein-1 (4EBP-1), the latter resulting in release of the eukaryotic initiation f ... Cited by 4 - Related articles - All 5 versions
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