J Ambati - Investigative Ophthalmology & Visual Science, 2011 - ARVO It is notable that the first human trials of siRNAs were conducted in the eye. siRNAs targeting VEGF-A (bevasiranib) or one of its receptors VEGFR-1 (siRNA-027/AGN 211745) were tested as intravitreously administered drug candidates in clinical trials in patients with CNV due ... Related articles - All 2 versions
[HTML] from nih.govK Steczkiewicz, MT Zimmermann… - Proceedings of the …, 2011 - National Acad Sciences Telomerases constitute a group of specialized ribonucleoprotein enzymes that remediate chromosomal shrinkage resulting from the “end-replication” problem. Defects in telomere length regulation are associated with several diseases as well as with aging and cancer. Despite ... Related articles - All 4 versions
H Ito, M Ikeda, T Hasegawa… - Journal of the …, 2011 - ACS Publications A series of complementary molecular strands from 2-mer to 5-mer that are composed of m-terphenyl units bearing chiral/achiral amidine or achiral carboxyl groups linked via Pt(II) acetylide complexes were synthesized by sequential stepwise reactions, and their chiroptical properties on the ... Cited by 1 - Related articles - All 4 versions
[HTML] from nih.govH Fu, H Chen, X Zhang, Y Qu… - Nucleic acids …, 2011 - Oxford Univ Press Recent studies have revealed two distinct pathways for the DNA overstretching transition near 65 pN: 'unpeeling' of one strand from the other, and a transition from B-DNA to an elongated double-stranded 'S-DNA' form. However, basic questions concerning the dynamics of ... Cited by 1 - Related articles - All 5 versions
V Sartorelli… - Current topics in developmental biology, 2011 - ncbi.nlm.nih.gov Satellite cells (SCs) are the main source of adult skeletal muscle stem cells responsible for muscle growth and regeneration. By interpreting extracellular cues, developmental regulators control quiescence, proliferation, and differentiation of SCs by influencing coordinate gene ... Related articles - All 2 versions
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