T Hiekkalinna, AA Schäffer, B Lambert… - Human …, 2011 - content.karger.com A decade ago, there was widespread enthusiasm for the prospects of genome-wide association studies to identify common variants related to common chronic diseases using samples of unrelated individuals from populations. Although technological advancements allow us to query ...
NM Laird… - The Fundamentals of Modern Statistical Genetics, 2011 - Springer In the absence of genetic data at the molecular level, the results of heritability, aggregation and/or segregation analysis provided the first hints about the presence of genetic effects and, consequently, the existence of a disease gene. Without infor- mation on the etiology ...
LJ Palmer, NJ Timpson, DM Evans… - An Introduction to …, 2011 - books.google.com FOUR mapping complex disease genes using linkage disequilibrium and genome- wide association scans Lyle J. Palmer, Nicholas J. Timpson, David M. Evans, George Davey Smith, Lon R. Cardon Summary Remarkable advances have occurred recently in our ability to detect genetic ... Related articles
F Marroni, S Pinosio, G Zaina, F Fogolari… - Tree Genetics & …, 2011 - Springer Abstract Cinnamyl alcohol dehydrogenase (CAD) is involved in the biosynthesis of lignin, a component of plant cell wall which negatively impacts paper pulp processing and biomass fermentation to ethanol. Transgenic poplars with depressed CAD activity show structural alterations of ... Cited by 1 - Related articles
PC Matthews, E Adland, J Listgarten… - The Journal of …, 2011 - Am Assoc Immnol The potential contribution of HLA-A alleles to viremic control in chronic HIV type 1 (HIV-1) infection has been relatively understudied compared with HLA-B. In these studies, we show that HLA-A*7401 is associated with favorable viremic control in extended southern African ... Cited by 2 - Related articles - All 3 versions
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