HJ Kim, T Sato, B Rodríguez-Iturbe… - Journal of Pharmacology …, 2011 - ASPET The Imai rat is a model of spontaneous focal glomerulosclerosis, which leads to heavy proteinuria, hyperlipidemia, hypertension, and progressive renal failure. Treatment with AT1 blockers (ARBs) ameliorates proteinuria, hyperlipidemia, and nephropathy in this model. ... Related articles
C Wei, S El Hindi, J Li, A Fornoni, N Goes… - Nature Medicine, 2011 - nature.com Focal segmental glomerulosclerosis (FSGS) is a cause of proteinuric kidney disease, compromising both native and transplanted kidneys. Treatment is limited because of a complex pathogenesis, including unknown serum factors. Here we report that serum soluble ... Cited by 1
B Smeets, C Kuppe, EM Sicking… - Journal of the …, 2011 - Am Soc Nephrol The pathogenesis of the development of sclerotic lesions in focal segmental glomerulosclerosis (FSGS) remains unknown. Here, we selectively tagged podocytes or parietal epithelial cells (PECs) to determine whether PECs contribute to sclerosis. In three distinct models of ... All 3 versions
O Boyer, G Benoit, O Gribouval, F Nevo… - Journal of the …, 2011 - Am Soc Nephrol The recent identification of mutations in the INF2 gene, which encodes a member of the formin family of actin-regulating proteins, in cases of familial FSGS supports the importance of an intact actin cytoskeleton in podocyte function. To determine better the prevalence of INF2 ... Cited by 2 - Related articles - All 4 versions
沪公网安备号：31010402006960 （网站）31010405000484 （蝌蝌APP）
安全保密
