C Korth… - US Patent 7,932,043, 2011 - Google Patents ... 276(20): 16711-16719.* Krasemann, S., et al. "Induction of Antibodies against Human Prion Proteins (PrP) by DNA-mediated Immunization of PrP0/0 Mice" J. Immunolog. ... "Biogenesis and Transmembrane Orientation of the CellularIsoform of the Scrapie Prion Protein" Mol. Cell. ... Related articles - All 3 versions
T Kuczius, J Kleinert, H Karch… - Journal of cellular …, 2011 - Wiley Online Library ...Cellular prion proteins of plt isolated from human blood were analyzed by immunoblotting with ... Plt PrP C revealed three characteristic protein bands detected with all antibodies which ... band with the lowest molecular mass represents the non-glycosylated isoform, whereas the ... Related articles - All 3 versions
K Delmouly, M Belondrade… - Journal of General …, 2011 - Soc General Microbiol ... medium alone, we observed a significant inhibitory effect on accumulation of the abnormal isoform of the ... labelled overnight at 4 °C in PBS with SAF32 antibody to detect PrP C on ...Cell lines that are chronically infected with prions, as well as cultures expressing variable amounts ... Related articles - All 4 versions
B Petsch, A Muller-Schiffmann, A Lehle… - Journal of …, 2011 - Am Soc Microbiol ... Prions (PrP Sc ), the abnormal conformational isoforms of the cellular prion protein (PrP C ), are responsible for invariably fatal neurodegenerative diseases of humans and animals (1, 35). ... 1986. Scrapie and cellularPrPisoforms are encoded by the same chromosomal gene. ... Related articles - All 4 versions
KA Barton… - The EMBO Journal, 2011 - nature.com ... misfolded proteins trigger cell death pathways is largely unknown, but some reports have suggested mediation by normal cellular prion protein (PrP... During prion diseases, PrP C is converted to an abnormal autocatalytic isoform, PrP Sc , which can accumulate in diffuse deposits ...
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