[PDF] from harvard.eduDM Knipe - Replicating Vaccines, 2011 - Springer Viral vaccines have traditionally been live, attenuated viruses, or inactivated virus/subunits. Herpes simplex virus (HSV) vaccine candidates based on inactivated viruses or subunits have not been effective thus far. In addition, attenuation of HSV to make a safe vaccine ... Related articles - All 3 versions
E Matsuo, CCP Celma, M Boyce… - Journal of …, 2011 - Am Soc Microbiol The reverse genetics technology for bluetongue virus (BTV) has been used in combination with complementing cell lines to recover defective BTV-1 mutants. To generate a potential disabled infectious single cycle (DISC) vaccine strain, we used a reverse genetics system to ...
S Paolucci, R Gulminetti, R Maserati… - Current HIV …, 2011 - ingentaconnect.com ... In vivo selection of stop codons in the RT gene resulted in the accumulation of replication- defectivevirus strains. ... In addition, the presence of replication defectivevirus variants might have played a major role in the slow progression to disease in this patient. ... Related articles - All 2 versions
EE Zumbrun… - Replicating Vaccines, 2011 - Springer Live attenuated vaccines represent the most successful approach for the prevention of alphaherpesvirus infections, including varicella zoster virus, pseudorabies virus, and equine herpes virus 1. It is reasonable to consider that live virus vaccines may also be effective for ... Related articles - All 2 versions
A Hiraguri, O Netsu, T Shimizu, T Uehara-Ichiki… - Archives of …, 2011 - Springer Abstract The nonstructural protein pC6 encoded by rice grassy stunt virus is thought to correspond functionally to the nonstructural protein pC4 of rice stripe virus, which can support viral cell-to-cell movement. In a trans-complementation experiment with a ... Related articles - All 4 versions
沪公网安备号：31010402006960 （网站）31010405000484 （蝌蝌APP）
安全保密
