RF Mullins, AD Dewald, LM Streb, K Wang… - Experimental Eye …, 2011 - Elsevier Data from human genetics, histopathology, and animal models reveal a major role for the complement system in the development of age-related macular degeneration (AMD). Genetic variations in the complement factor H (CFH) gene are associated with an elevated risk of AMD. In this ... All 2 versions
K Kunchithapautham… - Journal of Biological Chemistry, 2011 - ASBMB Uncontrolled activation of the alternative complement pathway and secretion of vascular endothelial growth factor (VEGF) are thought to be associated with age-related macular degeneration (AMD). Previously, we have shown that in RPE monolayers, oxidative-stress reduced ... Related articles
K Kunchithapautham… - Journal of Biological Chemistry, 2011 - ASBMB Uncontrolled activation of the alternative com- plement pathway and secretion of vascular en- dothelial growth factor (VEGF) are thought to be associated with age-related macular degene- ration (AMD). Previously, we have shown that in RPE monolayers, ... Related articles - All 2 versions
J Liu, P Jha, VV Lyzogubov, RG Tytarenko… - Journal of Biological …, 2011 - ASBMB Present study investigated the interactions among complement membrane attack complex (MAC), CCL2 and VEGF that occur in vivo during the development of choroidal neovascularization (CNV). We first investigated the sequential expression of MAC, CCL2 and VEGF during ... Related articles - All 2 versions
J Liu, P Jha, VV Lyzogubov, RG Tytarenko… - Journal of Biological …, 2011 - ASBMB The present study investigated the interactions among the complement membrane attack complex (MAC), CCL2, and VEGF that occur in vivo during the development of choroidal neovascularization (CNV). We first investigated the sequential expression of MAC, CCL2, and VEGF during ... Related articles
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