PCW Lee, ME Sowa, SP Gygi… - Molecular Cell, 2011 - Elsevier Vertebrates express two enzymes for activation of ubiquitin—UBA1, which is responsible for activation of the vast majority of E2 conjugating enzymes, and UBA6, which uses the dedicated E2, USE1. However, targets and E3s for UBA6-USE1 are unknown. Here, we ...
A Chatterjee, CM Johnson, CC Shu… - Proceedings of the …, 2011 - National Acad Sciences Convergent gene pairs with head-to-head configurations are widespread in both eukaryotic and prokaryotic genomes and are speculated to be involved in gene regulation. Here we present a unique mechanism of gene regulation due to convergent transcription from the ... Cited by 3 - Related articles - All 3 versions
M Smith, DR Mallin, JA Simon… - Journal of Biological Chemistry, 2011 - ASBMB The Drosophila protein Sex Comb on Midleg (Scm) is a member of the Polycomb group (PcG), a set of transcriptional repressors that maintain silencing of homeotic genes during development. Recent findings have identified PcG proteins both as targets for ... Cited by 1 - Related articles
[HTML] from nih.govJE Lee, MJ Sweredoski, RLJ Graham… - Molecular & Cellular …, 2011 - ASBMB The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble with Skp1-Cul1-RING to serve as the substrate specificity subunit of an SCF ubiquitin ligase complex. SCF activity is switched on by conjugation of the ubiquitin-like protein ... Cited by 2 - Related articles - All 6 versions
A Begitt, M Droescher, KP Knobeloch… - Blood, 2011 - ncbi.nlm.nih.gov The biological effects of interferon-γ (IFNγ) are mediated by the transcription factor STAT1. The activity of STAT1 is inhibited by SUMO conjugation. This occurs both directly through decreasing STAT1 tyrosine phosphorylation, and indirectly by facilitating STAT1 dephosphorylation ... Cited by 1