[PDF] from uab.eduSM Rowe, P Sloane, LP Tang, K Backer… - Journal of Molecular …, 2011 - Springer Abstract Certain aminoglycosides are capable of inducing “translational readthrough” of premature termination codons (PTCs). However, toxicity and relative lack of efficacy deter treatment with clinically available aminoglycosides for genetic diseases caused by PTCs, ...
D Landman, P Kelly, M Bäcker… - Journal of …, 2011 - Br Soc Antimicrob Chemo Results Resistance to the traditional aminoglycosides was common in the collection of A. baumannii. ACHN-490 possessed superior activity against these isolates, with an MIC 50 value of 8 mg/L. In P. aeruginosa, the activity of ACHN-490 was similar to that of amikacin (MIC ... Cited by 6 - Related articles - All 4 versions
C Meyer-Schwesinger, C Lange, V Brocker… - The American Journal of …, 2011 - Elsevier A key event in the progression of glomerular disease is podocyte loss that leads to focal and segmental glomerulosclerosis (FSGS). Because adult podocytes are postmitotic cells, podocyte replacement by bone marrow–derived progenitors could prevent podocytopenia ... Related articles - All 4 versions
R Allam, MN Darisipudi… - The Journal of …, 2011 - Am Assoc Immnol Clinical use of antibiotics is based on their capacity to inhibit bacterial growth via bacteriostatic or bacteriocidal effects. In this article, we show that the aminoglycoside antibiotic neomycin, the cyclic lipopeptide antibiotic polymyxin B, and the cyclic peptide antibiotics gramicidin and ... Cited by 3 - Related articles - All 3 versions
S Fraud… - Antimicrobial agents and chemotherapy, 2011 - Am Soc Microbiol Exposure to reactive oxygen species (ROS) (eg, peroxide) was shown to induce expression of the PA5471 gene, which was previously shown to be required for antimicrobial induction of the MexXY components of the MexXY-OprM multidrug efflux system and aminoglycoside ... Cited by 1 - Related articles - All 4 versions