YH Paik, K Iwaisako, E Seki, S Inokuchi… - …, 2011 - Wiley Online Library Although NOX plays an important role in HSC activation and hepatic fibrosis, how various NOX homologues expressed in different hepatic cell types contribute to hepatic fibrogenesis is unknown. The purpose of the present study was to investigate the contributory role of ... Cited by 1 - Related articles - All 3 versions
C Brenner - Journal of Biological Chemistry, 2011 - ASBMB In a study aimed at identifying factors contributing to nicotinamide riboside (NmR) metabolism in yeast, Drs. Lu and Lin prepared a cellular extract by bead-beating in ice-cold 50 mm ammonium acetate (1). In Figs. 1–4, they added this extract to an NmR-dependent yeast strain and ... Related articles - All 3 versions
V Audrito, T Vaisitti, D Rossi, D Gottardi, G D'Arena… - Cancer Research, 2011 - AACR Because of its relatively indolent clinical course, chronic lymphocytic leukemia (CLL) offers a versatile model for testing novel therapeutic regimens and drug combinations. Nicotinamide is the main NAD + precursor and a direct inhibitor of four classes of enzymes, including ... Cited by 1 - Related articles - All 3 versions
R Tao, D Wei, H Gao, Y Liu, RA DePinho… - Journal of Biological …, 2011 - ASBMB FoxO transcription factors have been implicated in lipid metabolism; however, the underlying mechanisms are not well understood. Here, in an effort to elucidate such mechanisms, we examined the phenotypic consequences of liver-specific deletion of three members of the FoxO ... Related articles - All 4 versions
EH Hong, HS Yun, J Kim, HD Um, KH Lee… - Journal of Biological …, 2011 - ASBMB Although much is known about interleukin (IL)-1β and its role as a key mediator of cartilage destruction in osteoarthritis, only limited information is available on IL-1β signaling in chondrocyte dedifferentiation. Here, we have characterized the molecular mechanisms leading to the ...
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